Overweight and seminal quality

Overweight and seminal quality: a study of 794 patients
Fertility and Sterility
Volume 94, Issue 5 , Pages 1739-1743, October 2010.
Ana C. Martini, Andrea Tissera, Daniel Estofán, Rosa I. Molina, Arnaldo Mangeaud, Marta Fiol de Cuneo, Rubén D. Ruiz.

To evaluate sperm quality, levels of markers of epididymal and accessory gland function, and T in semen from men grouped according to their body mass index (BMI).

Blind prospective study.

Andrology and reproduction laboratory in Cordoba, Argentina (2006–2007).

Seven hundred ninety-four men.


Main Outcome Measure(s)
In semen samples, sperm quality (volume, density, motility, morphology, viability, hypoosmotic swell test, and nuclear maturity) and levels of neutral alpha-glucosidase, fructose, citric acid and T.

Multivariate analysis showed a negative association between BMI and motility, rapid motility and neutral alpha-glucosidase levels, and a positive association between BMI and seminal fructose levels. No associations were found among BMI and sperm concentration, the other parameters evaluated, or seminal T levels.

Results found in our study support a deleterious effect of obesity on seminal quality, probably by alterations in the function of the epididymis (i.e., in epididymal maturation).

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